MSDS Number: P0082 * * * * * Effective Date: 06/19/07 * * * * *
Supercedes: 05/07/07

Pancreatin

1. Product Identification

Synonyms: Diastase vera; Pandrotanon; Zypanar
CAS
No.: 8049-47-6
Molecular Weight: Not applicable.

Chemical Formula: Not applicable.
Product Codes: 2840

2. Composition/Information on Ingredients

Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------------ ---------

Pancreatin 8049-47-6 90 - 100% Yes

3. Hazards Identification

Emergency Overview
--------------------------

CAUTION! IRRITANT. CAUSES IRRITATION TO EYES, RESPIRATORY SYSTEM AND
SKIN. HANDLE WITH CARE, GENERALLY IN KEEPING WITH SAFE LABORATORY PRACTICES IS
RECOMMENDED.

SAF-T-DATA(tm) Ratings (Provided
here for your convenience)

-----------------------------------------------------------------------------------------------------------

Health Rating: 2 - Moderate (Life)
Flammability Rating: 0 - None

Reactivity Rating: 0 - None
Contact Rating: 2 - Moderate
Lab
Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES
Storage
Color Code: Green (General Storage)

Potential Health Effects
----------------------------------

Inhalation:
Irritation of mucous membranes and upper
respiratory tract.
Ingestion:
Allergic reaction may develop.

Skin Contact:
Irritation.
Eye Contact:

Irritation.
Chronic Exposure:
Prolonged exposure may cause
skin irritation. allergic reaction may develop, May cause dermatitis.

Aggravation of Pre-existing Conditions:
Persons with
pre-existing skin disorders or eye dermatitis. asthma.

4. First Aid Measures

Inhalation:
If a person breathes in large amounts, move
the exposed person to fresh air.
Ingestion:
If large amounts
were swallowed, give water to drink and get medical advice.
Skin
Contact:
In case of contact, immediately wash skin with plenty of soap
and water for at least 15 minutes.
Eye Contact:
In case of eye
contact, immediately flush with plenty of water for at least 15 minutes.

5. Fire Fighting Measures

Fire:
Not expected to be a fire hazard.

Explosion:
None identified.
Fire Extinguishing
Media:
Use extinguishing media appropriate for surrounding fire.

Special Information:
Firefighters should wear proper protective
equipment and self-contained breathing apparatus with full facepiece operated
in positive pressure mode.

6. Accidental Release Measures

Clean-up personnel may require respiratory protection from dust.
Vacuuming or wet sweeping may be used to avoid dust dispersal. Flush area with
water. Prevent run-off from entering drains, sewers, or
streams.

7. Handling and Storage

Keep container tightly closed. Store in a cool, dry,
well-ventilated area. Do not expose to heat. Refrigeration is recommended for
extended storage periods. Avoid creating dust. Containers of this material may
be hazardous when empty since they retain product residues (dust, solids);
observe all warnings and precautions listed for the product.

8. Exposure Controls/Personal Protection

Airborne Exposure Limits:
None established.

Ventilation System:
In general, dilution ventilation is a
satisfactory health hazard control for this substance. However, if conditions
of use create discomfort to the worker, a local exhaust system should be
considered.
Personal Respirators (NIOSH Approved):
For
conditions of use where exposure to dust or mist is apparent and engineering
controls are not feasible, a particulate respirator (NIOSH type N95 or better
filters) may be worn. If oil particles (e.g. lubricants, cutting fluids,
glycerine, etc.) are present, use a NIOSH type R or P filter. For emergencies
or instances where the exposure levels are not known, use a full-face
positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators
do not protect workers in oxygen-deficient atmospheres.
Skin
Protection:
Wear protective gloves and clean body-covering clothing.

Eye Protection:
Use chemical safety goggles and/or full face
shield where dusting or splashing of solutions is possible. Maintain eye wash
fountain and quick-drench facilities in work area.

9. Physical and Chemical Properties

Appearance:
Off-white Powder.
Odor:

Characteristic odor.
Solubility:
Slight (0.1-1%)

Specific Gravity:
No information found.
pH:
No
information found.
% Volatiles by volume @ 21C (70F):
0

Boiling Point:
No information found.
Melting Point:

No information found.
Vapor Density (Air=1):
Not
applicable.
Vapor Pressure (mm Hg):
Not applicable.

Evaporation Rate (BuAc=1):
No information found.

10. Stability and Reactivity

Stability:
Stable under ordinary conditions of use and
storage.
Hazardous Decomposition Products:
Carbon monoxide,
carbon dioxide.
Hazardous Polymerization:
Will not occur.

Incompatibilities:
Acids, oxidizers.
Conditions to
Avoid:
Heat.

11. Toxicological Information

--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Pancreatin (8049-47-6) No No None

12. Ecological Information

Environmental Fate:
No information found.

Environmental Toxicity:
No information found.

13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be
managed in an appropriate and approved waste disposal facility. Processing,
use or contamination of this product may change the waste management options.
State and local disposal regulations may differ from federal disposal
regulations. Dispose of container and unused contents in accordance with
federal, state and local requirements.

14. Transport Information

Not regulated.

15. Regulatory Information

--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Pancreatin (8049-47-6) Yes Yes No Yes

--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Pancreatin (8049-47-6) Yes No No Yes

--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Pancreatin (8049-47-6) No No No No

--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Pancreatin (8049-47-6) No No No

Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: No Chronic: No Fire: No Pressure: No
Reactivity: No (Pure / Solid)

Australian Hazchem Code: None allocated.

Poison Schedule: None allocated.
WHMIS:
This MSDS
has been prepared according to the hazard criteria of the Controlled Products
Regulations (CPR) and the MSDS contains all of the information required by the
CPR.

16. Other Information

NFPA Ratings: Health: 1 Flammability: 1
Reactivity: 0
Label Hazard Warning:
CAUTION! IRRITANT.
CAUSES IRRITATION TO EYES, RESPIRATORY SYSTEM AND SKIN. HANDLE WITH CARE,
GENERALLY IN KEEPING WITH SAFE LABORATORY PRACTICES IS RECOMMENDED.

Label Precautions:
During use avoid contact with eyes, skin,
clothing. Wash thoroughly after handling. When not in use keep in tightly
closed container.
Label First Aid:
If a person breathes in
large amounts, move the exposed person to fresh air. In case of contact,
immediately flush eyes or skin with plenty of water for at least 15 minutes.
Remove contaminated clothing and shoes. Wash clothing before reuse.

Product Use:
Laboratory Reagent.
Revision
Information:
MSDS Section(s) changed since last revision of document
include: 3.
Disclaimer:

************************************************************************************************

Mallinckrodt Baker, Inc. provides the information contained herein in
good faith but makes no representation as to its comprehensiveness or
accuracy. This document is intended only as a guide to the appropriate
precautionary handling of the material by a properly trained person using this
product. Individuals receiving the information must exercise their independent
judgment in determining its appropriateness for a particular purpose.
MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER
EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF
MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE
INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS.
ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES
RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.

************************************************************************************************

Prepared by: Environmental Health & Safety
Phone Number:
(314) 654-1600 (U.S.A.)